Meet overqualified, underemployed, 24-year-old Andy French. Ambition: to be a cartoonist. Occupation: salesman at Waterbed World. Hobby: Where's the party? But responsibility soon knocks on the door of the loft apartment Andy shares with two fellow slackers when Kevin, a nerdy 17 -year-old who wears his SAT score on his shirt and his admiration for big brother Andy on his sleeve, moves in. And, for good measure, so does the French family's dog. Friends, roomies, canines, countrymen: lend me your beers. They're all part of the daze of Andy's life.

Nemo, un jeune poisson-clown intrépide est capturé puis plongé dans l'aquarium d'un cabinet dentaire. Marin, son père, et Dory, un poisson-chirurgien bleu sympathique mais tête-en-l'air, entament un long périple pour le retrouver. Ils croiseront en chemin une éclectique faune tropicale plus ou moins bien intentionnée. Sauront-ils retrouver la piste de Nemo ?